A PC-PROGRAM FOR THE ANALYSIS OF ELECTROPHYSIOLOGICAL SIGNALS RECORDED FROM THE MAMMALIAN EYE

Background Electrophysiological measurements in the mammalian eye in vivo or in vitro, i.e. in the arterially perfused cat eye, require storage and analysis of a large amount of data: light-evoked signals, including the electroretinogram (ERG) and the optic nerve response (ONR) are stimulus-related and have to be measured in a triggered mode, whereas the DC-standing potential and now rate of perfusion medium should be measured continuously. Method and result In order to facilitate the analysis of these various signals, we developed a computer program, that allows an on-line data analysis and a trend indication for pharmacologically induced changes in signal size as well as efficient storage. The flexible system is based on a ''labview'' program, the application and efficiency of which are discussed.