PRODRUGS OF L-CYSTEINE AS PROTECTIVE AGENTS AGAINST ACETAMINOPHEN-INDUCED HEPATOTOXICITY - 2-(POLYHYDROXYALKYL)THIAZOLIDINE-4(R)-CARBOXYLIC AND 2-(POLYACETOXYALKYL)THIAZOLIDINE-4(R)-CARBOXYLIC ACIDS

被引：116

作者：

ROBERTS, JC

NAGASAWA, HT

ZERA, RT

FRICKE, RF

GOON, DJW

机构：

[1] UNIV MINNESOTA,DEPT MED CHEM,MINNEAPOLIS,MN 55455

[2] VET ADM MED CTR,MED RES LABS,MINNEAPOLIS,MN 55417

[3] HENNEPIN CTY MED CTR,MINNEAPOLIS,MN 55415

[4] USA,MED RES INST INFECT DIS,FREDERICK,MD 21701

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 10期

关键词：

D O I：

10.1021/jm00393a034

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1891 / 1896

页数：6

共 36 条

[1] CHEMICAL ASPECTS OF SELECTIVE TOXICITY [J].

ALBERT, A .

NATURE, 1958, 182 (4633) :421-423

[2]

BOGNAR R, 1970, LIEBIGS ANN CHEM, V738, P68

[3]

BOGNAR R, 1976, LIEBIGS ANN CHEM, P450

[4]

BOGNAR R, 1975, LIEBIGS ANN CHEM, P1637

[5]

CORCORAN GB, 1985, J PHARMACOL EXP THER, V232, P864

[6]

Fischer E., 1894, BER, V27, P673

[7]

GRIFFITH OW, 1979, J BIOL CHEM, V254, P7558

[8]

Hinson JA., 1980, REV BIOCHEM TOXICOL, V2

[9] EQUILIBRIA FOR REACTION OF CYSTEINE AND DERIVATIVES WITH FORMALDEHYDE AND PROTONS [J].

KALLEN, RG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (23) :6227-&

[10]

KORBER F, 1968, Z KLIN CHEM KLIN BIO, V6, P289

← 1 2 3 4 →