A MODIFIED SYNTHESIS OF (+/-)-BETA-ARYLLACTIC ACIDS

被引：55

作者：

WONG, HNC

XU, ZL

CHANG, HM

LEE, CM

机构：

[1] CHINESE UNIV HONG KONG,CHINESE MED MAT RES CTR,SHA TIN,HONG KONG

[2] CHINESE UNIV HONG KONG,DEPT BIOCHEM,SHA TIN,HONG KONG

来源：

SYNTHESIS-STUTTGART | 1992年 / 08期

关键词：

D O I：

10.1055/s-1992-26228

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of racemic forms of the reportedly active principle of Danshen, namely (+/-)-beta-(3,4-dihydroxyphenyl)lactic acid [(+/-)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid] and its seven racemic derivatives is reported.

引用

页码：793 / 797

页数：5

共 25 条

[1]

BERENYI E, 1971, Patent No. 2052954

[2] A METHOD OF SYNTHESIS OF PHENYLLACTIC ACID AND SUBSTITUTED PHENYLLACTIC ACIDS [J].

BUBL, EC ;

BUTTS, JS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1951, 73 (10) :4972-4972

[3]

Buck J. S., 1943, ORG SYNTH, P55

[4] STUDIES ON THEORETICAL PSYCHOTOGENS - SYNTHESIS OF O-METHYLATED ANALOGS OF CATECHOLAMINE NEUROTRANSMITTERS AND METABOLIC PRECURSORS [J].

BUTTERICK, JR ;

UNRAU, AM .

CANADIAN JOURNAL OF CHEMISTRY, 1974, 52 (16) :2873-2879

[5]

Caesar P. D., 1963, ORG SYNTH, V4, P695

[6]

CHANG HM, 1990, J CHEM RES-S, P114

[7] STRUCTURE ELUCIDATION AND TOTAL SYNTHESIS OF NEW TANSHINONES ISOLATED FROM SALVIA-MILTIORRHIZA BUNGE (DANSHEN) [J].

CHANG, HM ;

CHENG, KP ;

CHOANG, TF ;

CHOW, HF ;

CHUI, KY ;

HON, PM ;

TAN, FWL ;

YANG, Y ;

ZHONG, ZP ;

LEE, CM ;

SHAM, HL ;

CHAN, CF ;

CUI, YX ;

WONG, HNC .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (11) :3537-3543

[8] COMPOUNDS FROM DANSHEN .4. STRUCTURE ACTIVITY RELATIONSHIP OF MILTIRONE, AN ACTIVE CENTRAL BENZODIAZEPINE RECEPTOR LIGAND ISOLATED FROM SALVIA-MILTIORRHIZA BUNGE (DANSHEN) [J].

CHANG, HM ;

CHUI, KY ;

TAN, FWL ;

YANG, Y ;

ZHONG, ZP ;

LEE, CM ;

SHAM, HL ;

WONG, HNC .

JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (05) :1675-1692

[9]

CHANG HM, 1990, J CHEM RES M, P877

[10]

CHEN ZX, 1981, CHIN J CHIN PHARM B, V16, P536

← 1 2 3 →