A CASE-CONTROL STUDY ON HUMAN IMMUNODEFICIENCY VIRUS-1 (HIV-1) INFECTION AS A RISK FACTOR FOR TUBERCULOSIS AND LEPROSY IN WESTERN KENYA

被引：18

作者：

OREGE, PA

FINE, PEM

LUCAS, SB

OBURA, M

OKELO, C

OKUKU, P

WERE, M

机构：

[1] LONDON SCH HYG & TROP MED, DEPT EPIDEMIOL & POPULAT SCI, LONDON, ENGLAND

[2] UNIV COLL & MIDDLESEX SCH MED, LONDON, ENGLAND

来源：

TUBERCLE AND LUNG DISEASE | 1993年 / 74卷 / 06期

关键词：

D O I：

10.1016/0962-8479(93)90080-H

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A case control study was undertaken in Western Kenya from April 1989 to August 1990 to evaluate HIV-1 infection as a risk factor for tuberculosis and leprosy. The study involved 144 newly diagnosed sputum smear positive tuberculosis cases with 432 age, sex and neighbourhood-matched controls, and 132 diagnosed leprosy cases with 384 matched controls. Odds ratios obtained by conditional logistic regression (matched) analysis were 4.9 (95% CI 2.6, 6.8), and 1.8 (95% CI 0.9, 3.2), for the association between HIV-1 and tuberculosis and leprosy respectively. Approximately 31% of tuberculosis cases among males, and 11% of cases among females, were attributable to HIV infection.

引用

页码：377 / 381

页数：5

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