PROSTAGLANDINS IN HUMAN UMBILICAL CIRCULATION AT BIRTH

被引：35

作者：

MITCHELL, MD

BRUNT, J

BIBBY, J

FLINT, APF

ANDERSON, ABM

TURNBULL, AC

机构：

[1] Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Oxford, Headington

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1978年 / 85卷 / 02期

关键词：

D O I：

10.1111/j.1471-0528.1978.tb10463.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Prostaglandin E (PGE), prostaglandin F (PGF) and 13, 14‐dihydro‐15‐keto‐prostaglandin F (PGFM) have been measured in umbilical cord plasma obtained immediately after delivery of the baby before clamping of the cord. In general the prostaglandin levels followed the pattern PGFM>PGE>PGF. A significant arterio‐venous difference was demonstrated only for PGE with raised venous levels (P<0.01). In cord blood samples obtained from infants whose mothers had received epidural anaesthesia, no arterio‐venous difference for PGE could be demonstrated although the mean levels were not significantly different from controls. The concentrations of prostaglandins in Umbilical cord plasma proximal to the placenta were found to rise continuously from the time of delivery of the baby with no significant changes after cord clamping or placental delivery. The possible physiological significance of these findings is discussed. Copyright © 1978, Wiley Blackwell. All rights reserved

引用

页码：114 / 118

页数：5

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