AN EFFICIENT SYNTHESIS OF RACEMIC AND OPTICALLY-ACTIVE TELLUROMETHIONINE

被引：11

作者：

SILKS, LA ^{[1
]}

BOLES, JO ^{[1
]}

MODI, BP ^{[1
]}

DUNLAP, RB ^{[1
]}

ODOM, JD ^{[1
]}

机构：

[1] UNIV S CAROLINA,DEPT CHEM,COLUMBIA,SC 29208

来源：

SYNTHETIC COMMUNICATIONS | 1990年 / 20卷 / 10期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1080/00397919008052873

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A direct and efficient route for the construction of racemic and optically active L-telluromethionine (L-Te-Met) starting from the readily available hydrochloride salt of a-amino-y-butyrolactone and lithium methyltellurolate is described. The reaction has been successfully scaled up to afford gram quantities of L-Te-Met in 75-80% yield. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：1555 / 1562

页数：8

共 27 条

[1] REACTION BETWEEN BETA-PROPIOLACTONE AND SELENIUM-CONTAINING REAGENTS [J].