GAMMA-GLUTAMYL TRANSPEPTIDASE (GGT) - EARLY MARKER FOR HEPATOCARCINOGENS IN RATS

被引：29

作者：

BOELSTERLI, U ^{[1
]}

机构：

[1] UNIV ZURICH,CH-8603 SCHWERZENBACH,SWITZERLAND

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1979年 / 1卷 / 02期

关键词：

D O I：

10.1016/0165-6147(79)90018-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Rat hepatocytes acquire a high GGT activity early during treatment with various hepatocarcinogens. Experimental models strongly suggest that this biochemical feature is a carcinogen-related induction of a fetal-like enzyme normally repressed in the adult state. © 1979.

引用

页码：47 / 49

页数：3

共 20 条

[1]

BOELSTERLI U, UNPUBLISHED

[2]

BRAUN JP, 1977, ANN BIOL CLIN-PARIS, V35, P433

[3]

CAMERON R, 1978, CANCER RES, V38, P823

[4] GAMMA-GLUTAMYLTRANSPEPTIDASE ACTIVITY IN NORMAL, REGENERATING AND MALIGNANT HEPATOCYTES [J].