AN ANTIVIRAL SESQUITERPENE HYDROQUINONE FROM THE MARINE SPONGE STRONGYLOPHORA-HARTMANI

被引：46

作者：

WRIGHT, AE

RUETH, SA

CROSS, SS

机构：

[1] Division of Biomedical Marine Research, Harbor Branch Oceanographic Institution, Ft. Pierce, FL 34946

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 04期

关键词：

D O I：

10.1021/np50076a032

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new sesquiterpene hydroquinone 1, which we call strongylin A, was isolated from the marine sponge Strogylophora hartmani. Its structure was determined through spectroscopic methods, including 2D-C-13 homonuclear correlation spectroscopy (INADEQUATE). Both 1 and its acetate derivative are active in in vitro assays against the P-388 tumor cell line and influenza strain PR-8.

引用

页码：1108 / 1111

页数：4

共 9 条

[1]

ALLEY MC, 1988, CANCER RES, V48, P589

[2] AN IMPROVED METHOD FOR HETERONUCLEAR CHEMICAL-SHIFT CORRELATION BY TWO-DIMENSIONAL NMR [J].