FARM-GRADE CHLORPYRIFOS (DURMET) IS GENOTOXIC IN SOMATIC AND GERM-LINE CELLS OF DROSOPHILA

被引：19

作者：

PATNAIK, KK

TRIPATHY, NK

机构：

[1] Department of Zoology, Berhampur University, Berhampur

来源：

MUTATION RESEARCH | 1992年 / 279卷 / 01期

关键词：

DURMET; INSECTICIDE; DROSOPHILA WING MOSAIC TEST; DROSOPHILA SEX-LINKED RECESSIVE LETHAL TEST;

D O I：

10.1016/0165-1218(92)90261-W

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The mutagenic potential of Durmet, a farm-grade formulation of chlorpyrifos, was studied in the Drosophila wing mosaic and sex-linked recessive lethal tests. Larvae of the 2nd or 3rd instar carrying suitable recessive genetic markers on chromosome 3 were exposed to different concentrations of the insecticide and the frequency of induction of mutant mosaic spots on the wings was noted. The Basc technique was followed to study the induction of sex-linked recessive lethals. On the basis of the frequency of induction of mosaic wing spots and sex-linked recessive lethals, it is concluded that Durmet is genotoxic in somatic cells as well as germ cells of Drosophila.

引用

页码：15 / 20

页数：6

共 30 条

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