PROLONGED DEPRESSION OF HEPATIC-MICROSOMAL DRUG-METABOLISM AND HEMOPROTEIN LEVELS FOLLOWING A SINGLE DOSE OF 1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA (CCNU)

被引：8

作者：

LITTERST, CL ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,PROGRAM DEV THERAPEUT,BETHESDA,MD 20205

来源：

BIOCHEMICAL PHARMACOLOGY | 1981年 / 30卷 / 09期

关键词：

D O I：

10.1016/0006-2952(81)90050-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1014 / 1016

页数：3

共 17 条

[1]

CARTER SK, 1968, CANCER CHEMOTH REP 3, V1, P115

[2]

CHENG CJ, 1972, CANCER RES, V32, P22

[3]

FALK JE, 1964, PORPHYRINS METALLOPO, P181

[4] SEPARATION OF HAEM INCORPORATION FROM PROTEIN SYNTHESIS IN LIVER [J].

GARNER, RC ;

MCLEAN, AEM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1969, 37 (06) :883-&

[5] HEPATOTOXICITY OF I-(2-CHLOROETHYL)-3-CYCLOHEXYL-I-NITROSOUREA(CCNU) IN DOGS - USE OF SERIAL PERCUTANEOUS LIVER BIOPSIES [J].

HENRY, MC ;

DAVIS, RD ;

SCHEIN, PS .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1973, 25 (03) :410-417

[6] SERUM ENZYMES IN HEPATOTOXICITY INDUCED BY CHLOROETHYLCYCLOHEXYL NITROSOUREA AND ARABINOFURANOSYL-6-MERCAPTOPURINE [J].

HENRY, MC ;

MARLOW, M .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1973, 24 (02) :250-255

[7]

HILL DL, 1975, CANCER RES, V35, P296

[8] HYDROXYLATION OF 1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA [J].

HILTON, J ;

WALKER, MD .

BIOCHEMICAL PHARMACOLOGY, 1975, 24 (23) :2153-2158

[9]

LEVIN W, 1975, BASIC THERAPEUTIC AS, P265

[10]

LITTERST CL, 1975, DRUG METAB DISPOS, V3, P259

← 1 2 →