THE PRESENCE OF HUMAN PAPILLOMAVIRUS IN SINONASAL PAPILLOMAS, DEMONSTRATED BY POLYMERASE CHAIN-REACTION WITH CONSENSUS PRIMERS

被引：19

作者：

BUCHWALD, C

FRANZMANN, MB

JACOBSEN, GK

LINDEBERG, H

机构：

[1] GENTOFTE UNIV HOSP,DEPT OTOLARYNGOL,GENTOFTE,DENMARK

[2] GENTOFTE UNIV HOSP,DEPT PATHOL,GENTOFTE,DENMARK

[3] AARHUS UNIV HOSP,DEPT OTOLARYNGOL,AARHUS,DENMARK

[4] AARHUS UNIV HOSP,DEPT PATHOL,AARHUS,DENMARK

来源：

HUMAN PATHOLOGY | 1993年 / 24卷 / 12期

关键词：

HUMAN PAPILLOMAVIRUS; POLYMERASE CHAIN REACTION; PAPILLOMA; SINONASAL;

D O I：

10.1016/0046-8177(93)90270-Q

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The frequency of human papillomavirus (HPV) in sinonasal papillomas seems to vary considerably. The highest frequencies have been reported by investigators using in situ DNA or RNA hybridization. Few studies have used polymerase chain reaction, and in these reports the frequency of HPV detection is rather low. We have investigated the presence of HPV in sinonasal papillomas using the polymerase chain reaction with a set of degenerated consensus primers, which amplify the vast majority of the known HPV types. Human papillomavirus was found in three of 14 papillomas. By in situ hybridization the same three papillomas were positive for HPV type 6 11. © 1993.

引用

页码：1354 / 1356

页数：3

共 16 条

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