CLINICAL PRESENTATION OF SPONTANEOUS PRIMARY HYPOTHYROIDISM IN ADULTS

被引：4

作者：

ALSULTAN, AI ^{[1
]}

LARBI, EB ^{[1
]}

MAGBOOL, G ^{[1
]}

KARIMA, T ^{[1
]}

BAGSHI, M ^{[1
]}

机构：

[1] KING FAISAL UNIV,COLL MED & MED SCI,DEPT INTERNAL MED,DAMMAM 31451,SAUDI ARABIA

来源：

ANNALS OF SAUDI MEDICINE | 1995年 / 15卷 / 02期

关键词：

D O I：

10.5144/0256-4947.1995.143

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a retrospective study of 309 cases of hypothyroidism seen dt King Fahd Hospital of the University (KFHU), Al-Khobar, 124 (90 Saudis and 34 non-Saudis) adult patients with spontaneous primary hypothyroidism satisfied the inclusion criteria for detailed analysis. Their male:female ratios for Saudis and non-Saudis were 1:4.6 and 1:3.9 respectively. The majority were diagnosed in their third and fourth decades. The prevalence of previously undiagnosed spontaneous and biochemically overt primary hypothyroidism in Saudis was 5.2/1000 females and 0.94/1000 males. FT4I was normal in 43 (35%)and low in 81 (65%). FT4I correlated with cold intolerance, constipation, dry skin, hoarseness, delayed reflex relaxation, and coarse and cold skin. In rank order, presenting symptoms in those with low FT4I were tiredness (56%), cold intolerance (38%), constipation, weight gain, menstrual disturbance - especially amenorrhea - (36% each), dry skin (35%), hoarseness (31%); signs were coarse skin (53%), delayed reflex relaxation (32%), cold skin and goiter (24% each). The above clinical findings may provide more data on this disease in this country.

引用

页码：143 / 147

页数：5