SYNTHESIS AND REACTIONS OF 4,6-DIMETHOXYINDOLE, AN UNUSUAL INDOLE SYSTEM

被引：34

作者：

BROWN, VH

SKINNER, WA

DEGRAW, JI

机构：

[1] Department of Pharmaceutical Chemistry, Stanford Research Institute, Menlo Park, California

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1969年 / 6卷 / 04期

关键词：

D O I：

10.1002/jhet.5570060414

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of 4,6‐dimethoxyindole is described. Formylation or oxalylation reactions gave substitution at position 7 rather than the usual 3‐substitution characteristic of other indoles. A synthesis of N,N‐dimethyl‐4,6‐dimethoxytryptamine is presented along with NMR data for 3 and 7‐substituted compounds in this series. Copyright © 1969 Journal of Heterocyclic Chemistry

引用

页码：539 / &

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