ACYLOXYLATION AT THE 4-POSITION OF AZETIDIN-2-ONES

被引：12

作者：

EASTON, CJ ^{[1
]}

LOVE, SG ^{[1
]}

WANG, P ^{[1
]}

机构：

[1] UNIV CANTERBURY,DEPT CHEM,CHRISTCHURCH 1,NEW ZEALAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 02期

关键词：

D O I：

10.1039/p19900000277

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The copper-catalysed reaction of azetidin-2-ones with t-butyl perbenzoate or peracetate affords the corresponding 4-benzoyloxy- and acetoxy-substituted β-lactams, respectively. N-Unsubstituted 4-acyloxyazetidinones can be synthesized by dearylation of the N-(4-methoxyphenyl)-substituted products with ceric ammonium nitrate. Acyloxylation of β-lactams that are monosubstituted at C-3 affords predominantly trans-products.

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页码：277 / 282

页数：6

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