HYDROQUINONE SIMULTANEOUSLY INDUCES INDOLE AMINE-2,3 DIOXYGENASE (IOD) AND INHIBITS TYROSINASE IN BUFO-MELANOSTICTUS

被引：2

作者：

CHAKRABORTY, AK ^{[1
]}

CHAKRABORTY, A ^{[1
]}

CHAKRABORTY, DP ^{[1
]}

机构：

[1] BOSE INST,DEPT CHEM,CALCUTTA 700009,W BENGAL,INDIA

来源：

LIFE SCIENCES | 1993年 / 52卷 / 21期

关键词：

D O I：

10.1016/0024-3205(93)90477-K

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Hydroquinone administration in Bufo melanostictus causes an induction of indole amine 2,3-dioxygenase in skin and liver while simultaneously inhibiting tyrosinase in these organs. The result is discussed with the reports of higher urinary excretion of abnormal indole metabolites including derivatives of anthranilic acid in vitiliginous subjects (Roychoudhury and Chakraborty, Clinica. Chim. Acta 22, 298, 1968; Kurbanov and Berezov, Vopr. Med. Khim. 22, 683, 1976).

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页码：1695 / 1698

页数：4

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