STYRENE EXPOSURE .2. PERCENTAGE STUDIES OF ABSORPTION, EXCRETION, AND METABOLISM BY HUMAN SUBJECTS

被引：15

作者：

CAPEROS, JR

HUMBERT, B

DROZ, PO

机构：

[1] UNIV NEUCHATEL, HYG IND LAB, CH-2000 NEUCHATEL, SWITZERLAND

[2] INTERFOOD SA, CH-2000 NEUCHATEL, SWITZERLAND

[3] INST UNIV MED SOCIALE & PREVENT, CH-1052 LE MONT, SWITZERLAND

来源：

INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 1979年 / 42卷 / 3-4期

关键词：

Biological monitoring; Half-life; Metabolites; excretion of; Percentage studies; Styrène; exposure to;

D O I：

10.1007/BF00377776

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To determine the quantities and percentages of styrene metabolites excreted in urine, 5 male subjects were given 5 controlled exposures to styrene, each of 8 h, at 206 and 103 ppm. About 92% of styrene is metabolized in the body. Of the amount absorbed, 54% is eliminated in the urine as phenylglyoxylic acid and 37% as mandelic acid. Neither difference between the individual subjects nor the exposure concentration seem greatly to influence elimination of the solvent. These urinary metabolites may be used as biological indicators of occupational exposure to styrene.

引用

页码：223 / 230

页数：8

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