THE 3-HYDROXY GROUP OF LANOSTEROL IS ESSENTIAL FOR ORIENTING THE SUBSTRATE IN THE SUBSTRATE SITE OF CYTOCHROME-P-45014DM (LANOSTEROL 14-ALPHA-DEMETHYLASE)

被引：33

作者：

AOYAMA, Y

YOSHIDA, Y

SONODA, Y

SATO, Y

机构：

[1] MUKOGAWA WOMENS UNIV,FAC PHARMACEUT SCI,11-68 KOSHIEN KYUBAN CHO,NISHINOMIYA,HYOGO 663,JAPAN

[2] KYORITSU COLL PHARMACEUT SCI,MINATO KU,TOKYO,JAPAN

来源：

关键词：

D O I：

10.1016/0005-2760(89)90198-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：209 / 213

页数：5

共 21 条

[1] AOYAMA Y, 1987, J BIOL CHEM, V262, P14260
[2] 14-ALPHA-DEMETHYLATION OF LANOSTEROL BY A RECONSTITUTED CYTOCHROME-P-450 SYSTEM FROM YEAST MICROSOMES
AOYAMA, Y
YOSHIDA, Y
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 85 (01) : 28 - 34
[3] NADPH-CYTOCHROME P-450 REDUCTASE OF YEAST MICROSOMES
AOYAMA, Y
YOSHIDA, Y
KUBOTA, S
KUMAOKA, H
FURUMICHI, A
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 185 (02) : 362 - 369
[4] AOYAMA Y, 1984, J BIOL CHEM, V259, P1661
[5] AOYAMA Y, 1987, BIOCHIM BIOPHYS ACTA, V922, P270
[6] AOYAMA Y, 1989, BIOCHIM BIOPHYS ACTA, V1001, P196
[7] AOYAMA Y, 1987, J BIOL CHEM, V262, P1239
[8] PURIFICATION AND CHARACTERIZATION OF LIVER MICROSOMAL CYTOCHROME-P-450 FROM UNTREATED MALE-RATS
FUNAE, Y
IMAOKA, S
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 926 (03) : 349 - 358
[9] A SINGLE AMINO-ACID SUBSTITUTION CONVERTS CYTOCHROME-P450(14DM) TO AN INACTIVE FORM, CYTOCHROME-P450(SG1) - COMPLETE PRIMARY STRUCTURES DEDUCED FROM CLONED DNAS
ISHIDA, N
AOYAMA, Y
HATANAKA, R
OYAMA, Y
IMAJO, S
ISHIGURO, M
OSHIMA, T
NAKAZATO, H
NOGUCHI, T
MAITRA, US
MOHAN, VP
SPRINSON, DB
YOSHIDA, Y
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 155 (01) : 317 - 323
[10] JONES E R H, 1973, Pure and Applied Chemistry, V33, P39, DOI 10.1351/pac197333010039