EFFECT OF VAGUS NERVE-STIMULATION ON THE SECRETORY-GRANULE VOLUME OF THE PRINCIPAL CELLS OF THE MOUSE GALLBLADDER EPITHELIUM

被引:4
作者
WAHLIN, T [1 ]
HULLIGER, M [1 ]
AXELSSON, H [1 ]
机构
[1] UMEA UNIV,DEPT PHYSIOL,S-90185 UMEA,SWEDEN
来源
ACTA PHYSIOLOGICA SCANDINAVICA | 1979年 / 106卷 / 03期
关键词
electrical stimulation; glycoprotein content; morphometry; Mouse gallbladder; nervus vagus; principal cells;
D O I
10.1111/j.1748-1716.1979.tb06410.x
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Experiments in mice were performed in order to investigate whether vagal activity could affect glycoprotein secretion from gallbladder principal cells. This cell type was studied with the electron microscope in control animals and after electric stimulation of the right or left nervus vagus. The volume density of glycoprotein containing granules was determined using morphometry. It was found that stimulation of the left vagus nerve significantly reduced the relative cellular volume of secretory granules in the principal cells of the gallbladder. Right vagus stimulation was accompanied by a weak but insignificant increase in secretory granule content. It is suggested that the left vagus nerve may exert a direct influence on glycoprotein secretion from gallbladder principal cells. © 1979 Scandinavian Physiological Society
引用
收藏
页码:359 / 363
页数:5
相关论文
共 25 条
[1]  
AXELSSON H, 1978, 1978 P ANN M SCAND S, P21
[2]  
AXELSSON H, GASTROENTEROLOGY
[3]  
BELLI L, 1965, MINERVA CHIR, V11, P926
[4]  
BOUCHIER IA, 1965, GASTROENTEROLOGY, V49, P343
[5]   SOME OBSERVATIONS ON INNERVATION OF EXTRAHEPATIC BILIARY SYSTEM IN MAN [J].
BURNETT, W ;
GAIRNS, FW ;
BACSICH, P .
ANNALS OF SURGERY, 1964, 159 (01) :8-&
[6]  
FRESTON JW, 1969, GASTROENTEROLOGY, V57, P670
[7]  
HULTEN O, 1970, Acta Chirurgica Scandinavica, V136, P53
[8]  
Jemerin EE, 1938, P SOC EXP BIOL MED, V38, P139
[9]  
MCCREA DAE, 1924, J ANAT, V59, P18
[10]  
MESTER Z, 1953, Zentralbl Chir, V78, P1128