VILLAGORGIN-A AND VILLAGORGIN-B - NEW-TYPE OF INDOLE ALKALOIDS WITH ACETYLCHOLINE ANTAGONIST ACTIVITY FROM THE GORGONIAN VILLAGORGIA-RUBRA

被引：15

作者：

ESPADA, A

JIMENEZ, C

DEBITUS, C

RIGUERA, R

机构：

[1] UNIV SANTIAGO, FAC QUIM, DEPT QUIM ORGAN, E-15706 SANTIAGO, SPAIN

[2] UNIV A CORUNA, FAC CIENCIAS, DEPT QUIM FUNDAMENTAL & IND, E-15071 CORUNA, SPAIN

[3] ORSTOM, CTR NOUMEA, NOUMEA, NEW CALEDONIA

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(00)61563-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new indoloquinolizidine alkaloids incorporating an imidazol ring, villagorgin A and villagorgin B, along with caffeine, tryptamine, Nb-methyltryptamine, and 1, 2, 3, 4 tetrahydro-beta-carboline, were isolated from the gorgonian Villagorgia rubra, and determined by spectral data. Villagorgin A has a calmodulin-related antagonist activity.

引用

页码：7773 / 7776

页数：4

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