INHIBITION OF LIPOLYTIC PROCESSES IN RAT ADIPOSE TISSUE BY ANTIMALARIAL DRUGS

被引:74
作者
MARKUS, HB
BALL, EG
机构
[1] Department of Biological Chemistry, Harvard Medical School, Boston
关键词
D O I
10.1016/0005-2760(69)90045-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Lipolytic processes in vitro of rat epididymal fat pads are inhibited by the antimalarial drugs quinine, quinidine, quinacrine, chloroquine, hydroxychloroquine and primaquine. These compounds inhibit hormone activated lipolysis, the lipolytic activity of adipose tissue homogenates and the activity released into the medium by heparin. © 1969.
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页码:486 / &
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