SERIAL MAGNETIC-RESONANCE-IMAGING IN JUVENILE DERMATOMYOSITIS DELAYED NORMALIZATION

被引:16
作者
HUPPERTZ, HI [1 ]
KAISER, WA [1 ]
机构
[1] UNIV WURZBURG,INST RADIOL,WURZBURG,GERMANY
关键词
MAGNETIC RESONANCE IMAGING; JUVENILE DERMATOMYOSITIS;
D O I
10.1007/BF00300815
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Demonstration of myositis in juvenile dermatomyositis (JDM) has traditionally required the presence of two out of three objective findings including muscle enzyme studies, electromyography, and muscle biopsy. Magnetic resonance imaging (MRI) is considered another objective criterion and has been recommended for follow-up studies as well. We report on a 6-year-old girl with JDM, presenting with facial rash and proximal muscle weakness, in whom MRI, in conjunction with elevated creatinine kinase (CK) levels, was diagnostic, with an increased T2 signal of proximal muscles. MRI reflected exacerbation of myositis in spite of steroid therapy 2 weeks later, but failed to mirror normalization of muscle strength and CK values 10 weeks later. In fact, improvement of MRI followed clinical and laboratory normalization with a delay of 2 months. This possible delay should be considered when MRI is used to monitor the response to therapy.
引用
收藏
页码:127 / 129
页数:3
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