PROTECTIVE EFFECT OF POLYMYXIN-B SULFATE IN EXPERIMENTAL ENTEROBACTERIAL INFECTION IN MICE

被引：16

作者：

BANNATYNE, RM

CHEUNG, R

机构：

来源：

CANADIAN JOURNAL OF MICROBIOLOGY | 1979年 / 25卷 / 09期

关键词：

D O I：

10.1139/m79-153

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mouse model of intraperitoneal enterobacterial sepsis was used to evaluate the anti-endotoxic effect of polymyxin B sulfate. Single or multiple therapeutic doses of polymyxin, administered either before or after lethal challenge with Serratia marcescens, produced statistically and clinically significant protective effects.

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页码：995 / 998

页数：4

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