MODULATION OF HORMONE RESPONSE ELEMENTS BY PROMOTER ENVIRONMENT

被引：10

作者：

ROESLER, WJ ^{[1
]}

PARK, EA ^{[1
]}

KLEMM, DJ ^{[1
]}

LIU, JS ^{[1
]}

GURNEY, AL ^{[1
]}

VANDENBARK, GR ^{[1
]}

HANSON, RW ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV,DEPT BIOCHEM,CLEVELAND,OH 44106

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1990年 / 1卷 / 07期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

D O I：

10.1016/1043-2760(90)90082-E

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hormone response elements (HREs) are nucleotide sequences that confer onto promoters the ability to alter their transcriptional pace in response to hormones. Growing evidence indicates that the functional activity of HREs can be significantly modulated by their promoter environment, making it possible for genes containing the same HRE to display diversity in their responsiveness to a given hormone signal. © 1990.

引用

页码：347 / 351

页数：5

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