EXCITATORY EFFECTS OF THYROTROPIN-RELEASING-HORMONE (TRH) IN HYPOGLOSSAL MOTONEURONS

被引：46

作者：

REKLING, JC

机构：

[1] Institute of Neurophysiology, Copenhagen University, Copenhagen

来源：

BRAIN RESEARCH | 1990年 / 510卷 / 01期

关键词：

Excitatory postsynaptic potential; Guinea pig; Hypoglossal motoneuron; Thyrotropin-releasing hormone;

D O I：

10.1016/0006-8993(90)90749-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effect of thyrotropin-releasing hormone (TRH) was studied in 30 hypoglossal motoneurons from brainstem slices of guinea pigs. Bath application of TRH resulted in an increase of the spontaneous excitatory synaptic activity, depolarization of the neurons, increase of the input resistance and change of the duration of the falling phase of excitatory postsynaptic potentials. The depolarizing response and membrane conductance change was the result of a direct postsynaptic action of TRH, possibly mediated by a reduction of a potassium conductance. © 1990.

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收藏

页码：175 / 179

页数：5

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