EARLY AMNIOCENTESIS AND AMNIOTIC-FLUID ORGANIC-ACID LEVELS IN THE PRENATAL-DIAGNOSIS OF ORGANIC ACIDEMIAS

被引：18

作者：

COUDE, M ^{[1
]}

CHADEFAUX, B ^{[1
]}

RABIER, D ^{[1
]}

KAMOUN, P ^{[1
]}

机构：

[1] HOP NECKER ENFANTS MALAD,BIOCHIM MED LAB B,F-75743 PARIS 15,FRANCE

来源：

CLINICA CHIMICA ACTA | 1990年 / 187卷 / 03期

关键词：

Amino acid metabolism; Amniocentesis; Amniotic fluid; Inborn error; Methyl malonic acid; Prenatal diagnosis; Propionic acid;

D O I：

10.1016/0009-8981(90)90118-C

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Organic acids were studied in amniotic fluids taken by early amniocentesis between 6 to 12 weeks in control pregnancies. The prenatal diagnosis of methylmalonic acidemia and propionic acidemia could be made by the measurement of methylmalonic and methylcitric acid respectively in the amniotic fluid taken simultaneously with chorionic villi at the 11 th week of gestation. © 1990.

引用

页码：329 / 332

页数：4

共 7 条

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