QUANTITATION OF C-REACTIVE PROTEIN-LEVELS AND ERYTHROCYTE SEDIMENTATION-RATE AFTER SPINAL SURGERY

被引：95

作者：

THELANDER, U

LARSSON, S

机构：

[1] Department of Orthopaedic Surgery, University Hospital, Umea

来源：

SPINE | 1992年 / 17卷 / 04期

关键词：

C-REACTIVE PROTEIN; ERYTHROCYTE SEDIMENTATION RATE; SPINAL SURGERY; DISCECTOMY; FUSION;

D O I：

10.1097/00007632-199204000-00004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

C-reactive protein and erythrocyte sedimentation rate were prospectively measured after four types of uncomplicated spinal operations. In all patients, preoperative normal C-reactive protein (< 10 mg/L) increased, reaching peak levels on the second day after microdiscectomy (46 +/- 21 mg/L) and anterior fusion (70 +/- 23 mg/L), and at the third day after conventional discectomy (92 +/- 47 mg/L) and posterolateral intercorporal fusion (173 +/- 39 mg/L), with normalization in 5-14 days. Peak levels were not related to bleeding, transfusion, operation time, administered drugs, age, or sex. Erythrocyte sedimentation rate increased to peak levels about 5 days after surgery, followed by a slow and irregular decrease, and at 21-42 days after surgery often remained elevated. The rapid decline in C-reactive protein will probably be interrupted by a second rise or persisting elevation if infection occurs. C-reactive protein is presumably a better test than erythrocyte sedimentation rate for early detection of postoperative infection.

引用

页码：400 / 404

页数：5

共 22 条

[1]

Aalto K., Osterman K., Peltola H., Rasanen J., Changes in erythrocyte sedimentation rate and C-reactive protein after total hip arthroplasty, Clin Orthop, 184, pp. 118-120, (1984)

[2]

Bircher M.D., Tasker T., Crawshaw C., Mulholland R.C., Discitis following lumbar surgery, Spine, 13, pp. 98-102, (1988)

[3]

Boralessa H., De Beer F.C., Manchie A., Whitwam J.G., Pepys M.B., C-reactive protein in patients undergoing cardiac surgery, Anaesthesia, 41, (1986)

[4]

Carr W.P., Acute-phase proteins, Clinics in Rheumatic Diseases, 1, pp. 227-239, (1983)

[5]

Fischer C.L., Gill C., Forrester M.G., Nakamura R., Quantitation of “acute-phase proteins” postoperatively: Value in detection and monitoring of complications, Am J Clin Pathol, 66, pp. 840-846, (1976)

[6]

Grollmus J., Perkins R.K., Russel W., Erythrocyte sedimentation rate as a possible indicator of early disc space infection, Neurochirurgia, 17, pp. 30-35, (1974)

[7]

Guyer R.D., Collier R., Stith W.J., Discitis after discography, Spine, 13, pp. 1352-1354, (1988)

[8]

Kindmark C.-O., The concentration of C-reactive protein in sera from healthy individuals, Scand J Clin Lab Invest, 29, (1972)

[9]

Kock-Jensen C., Brandslund I., Sogaard I., Lumbar disc surgery and variations in C-reactive protein, erythrocyte sedimentation rate and the complement split product C 3 d, Acta Neurochir, 90, pp. 42-44, (1988)

[10]

Mallya R.K., De Beer F.C., Berry H., Correlation of clinical parameters of disease activity in rheumatoid arthritis with serum concentration of C-reactive protein and erythrocyte sedimentation rate, J Rheumatol, 9, (1982)

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