UNUSUAL DIASTEREOFACIAL SELECTIVITY IN THE MICHAEL ADDITION-REACTIONS OF LITHIATED 2-AMINOACETATES AND 2-ACETAMIDES TO ALPHA, BETA-UNSATURATED CARBONYL-COMPOUNDS

被引：8

作者：

KANEMASA, S ^{[1
]}

NOMURA, M ^{[1
]}

TAGUCHI, Y ^{[1
]}

机构：

[1] KYUSHU UNIV, INTERDISCIPLINARY GRAD SCH ENGN SCI, DEPT MOLEC SCI & TECHNOL, KASUGA, FUKUOKA 816, JAPAN

来源：

CHEMISTRY LETTERS | 1992年 / 09期

关键词：

D O I：

10.1246/cl.1992.1801

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Unusual diastereofacial selectivities are observed in the Michael addition reactions of lithiated aminoacetates and -acetamides to alpha,beta-unsaturated carbonyl acceptors. Lithiated (methylamino)acetates and -acetamides show opposite anti- and syn-selectivities, respectively, while lithiated (dialkylamino)acetates and -acetamides are both highly syn-selective.

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页码：1801 / 1804

页数：4

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