STRUCTURE-ACTIVITY RELATIONSHIP OF SOME CHLORINATED HYDROCARBONS

被引:102
作者
SATO, A
NAKAJIMA, T
机构
[1] Department of Hygiene, School of Medicine, Shinshu University, Matsumoto, Asahi
来源
ARCHIVES OF ENVIRONMENTAL HEALTH | 1979年 / 34卷 / 02期
关键词
D O I
10.1080/00039896.1979.10667371
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Partition coefficients of water/air, blood/air, oil/air, and oil/water for twenty chlorinated hydrocarbons, which were determined by means of a vial-equilibration method, were examined in relation to their chemical structures and threshold limit values (TLVs) recommended by the American Conference of Governmental Industrial Hygienists. The TLV was correlated closely with the blood/air partition coefficient and with the product of the water/air and the oil/air partition coefficient except for carbon tetrachloride and o-dichlorobenzene. A relation between partition coefficients and toxicity of these hydrocarbons is also described. © 1979 Taylor & Francis Group, LLC.
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页码:69 / 75
页数:7
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