NOVEL ANTIBIOTICS, FURAQUINOCIN-A AND FURAQUINOCIN-B - TAXONOMY, FERMENTATION, ISOLATION AND PHYSICOCHEMICAL AND BIOLOGICAL CHARACTERISTICS

被引：58

作者：

KOMIYAMA, K

FUNAYAMA, S

ANRAKU, Y

ISHIBASHI, M

TAKAHASHI, Y

OMURA, S

机构：

[1] KITASATO INST,5-9-1 SHIROKANE,MINATO KU,TOKYO 108,JAPAN

[2] KITASATO UNIV,SCH PHARMACEUT SCI,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 03期

关键词：

D O I：

10.7164/antibiotics.43.247

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two novel antibiotics, furaquinocins A and B were isolated from the culture broth of Streptomyces sp. KO-3988. These antibiotics possess cytocidal activities against HeLa S3 cells in vitro at concentrations of 3.1 μg/ml for A and 1.6 μg/ml for B. Neither substance possessed antimicrobial activities against Gram-positive and Gram-negative bacteria, fungi or yeast at a concentration of 1,000 μg/ml. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：247 / 252

页数：6

共 7 条

[1] STRUCTURES OF NOVEL ANTIBIOTICS, FURAQUINOCIN-A AND FURAQUINOCIN-B [J].