HYDROGEN TRANSFER FROM 4-R AND 4-S (4-H-3)NADH IN THE REDUCTION OF D,L-CIS-6,7-DIMETHYL-6,7(8H)-DIHYDROPTERIN WITH DIHYDROPTERIDINE REDUCTASE FROM HUMAN-LIVER AND SHEEP LIVER

被引：20

作者：

ARMAREGO, WLF

机构：

[1] Medical Chemistry Group, John Curtin School of Medical Research, Australian National University, Canberra

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 89卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)90970-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transfer of the 4-hydrogen atom from NADH onto a nitrogen atom of d,l-cis-6,7-dimethyl-6,7(8H)-dihydropterin was shown to take place stereospecifically from the B-face of NADH (transfer of the pro-S hydrogen atom) by using 4-R and 4-S (4-3H)NADH, and dihydropteridine reductase from human liver and sheep liver. © 1979.

引用

页码：246 / 249

页数：4

共 8 条

[1] ARMAREGO WLF, 1979, CHEM BIOL PTERIDINES, P1
[2] Arnold L J Jr, 1978, Methods Enzymol, V54, P223
[3] BLAKLEY RL, 1969, BIOCH FOLIC ACID REL, P229
[4] NAPHTHOQUINONE ADSORBENT FOR AFFINITY CHROMATOGRAPHY OF HUMAN DIHYDROPTERIDINE REDUCTASE
COTTON, RGH
JENNINGS, I
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1978, 83 (01): : 319 - 324
[5] HASEGAWA H, 1979, CHEM BIOL PTERIDINES, P183
[6] KAUFMAN S, 1964, J BIOL CHEM, V239, P332
[7] POPJAK G, 1969, METHOD ENZYMOL, V15, P393
[8] RAFTER GW, 1957, METHODS ENZYMOLOGY, V3, P881

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