EFFECTS OF 4-AMINOPYRIDINE IN MYASTHENIA-GRAVIS

被引：101

作者：

LUNDH, H ^{[1
]}

NILSSON, O ^{[1
]}

ROSEN, I ^{[1
]}

机构：

[1] UNIV LUND HOSP,DEPT CLIN NEUROPHYSIOL,S-22185 LUND,SWEDEN

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1979年 / 42卷 / 02期

关键词：

D O I：

10.1136/jnnp.42.2.171

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A new drug, 4-aminopyridine, was prepared for use in humans and tested by repeated injections in six patients with myasthenia gravis. The drug caused improvement of muscle strength and neuromuscular transmission as demonstrated by clinical observations and repetitive electrical nerve stimulation. The drug was effective in cases without any other treatment as well as in cases undergoing treatment with anticholinesterases. It is concluded that 4-aminopyridine may be of value as a supplementary drug in the treatment of myasthenia gravis.

引用

页码：171 / 175

页数：5

共 13 条

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