EFFICIENT DNA PAIRING IN A NEUROSPORA MUTANT DEFECTIVE IN CHROMOSOME-PAIRING

被引：16

作者：

FOSS, HM ^{[1
]}

SELKER, EU ^{[1
]}

机构：

[1] UNIV OREGON,INST MOLEC BIOL,EUGENE,OR 97403

来源：

MOLECULAR & GENERAL GENETICS | 1991年 / 231卷 / 01期

关键词：

NEUROSPORA; REPEAT-INDUCED POINT MUTATION (RIP); RECOMBINATION; SYNAPSIS; DNA PAIRING;

D O I：

10.1007/BF00293820

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A Neurospora crassa mutation, mei-2, affecting recombination and pairing of homologous chromosomes during meiosis, was characterized for its effect on repeat-induced point mutation (RIP). We found that RIP, which depends on recognition of DNA sequence homology, is not inhibited by mei-2, suggesting that the defect in chromosome pairing of this mutant is not due to a defect in DNA pairing and that DNA pairing is not dependent on chromosome pairing.

引用

页码：49 / 52

页数：4

共 25 条

[1] ANALYSIS OF WILD-TYPE AND RAD50 MUTANTS OF YEAST SUGGESTS AN INTIMATE-RELATIONSHIP BETWEEN MEIOTIC CHROMOSOME SYNAPSIS AND RECOMBINATION [J].