CEREBELLAR FORM OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY IN A PATIENT WITH CHRONIC-RENAL-FAILURE

被引：12

作者：

IRIE, T

KASAI, M

ABE, N

SETO, K

NAOHARA, T

KAWAMURA, K

HIGA, T

SANO, K

TAKAHASHI, H

NAGASHIMA, K

机构：

[1] Department of Internal Medicine, Sapporo Hokuyu Hospital, Artificial Organ Transplantation Hospital, Sapporo

[2] Departmcnt of Second Pathology, University of Hokkaido, Sapporo

来源：

INTERNAL MEDICINE | 1992年 / 31卷 / 02期

关键词：

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; CEREBELLAR SYMPTOM; CHRONIC RENAL FAILURE; IMPAIRED CELL-MEDIATED IMMUNITY; SOUTHERN BLOTTING OF DNA;

D O I：

10.2169/internalmedicine.31.218

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Progressive multifocal leukoencephalopathy (PML) developed in a 64-year-old woman who had undergone hemodialysis treatment due to chronic renal failure (CRF) for 6 yr. Her initial symptom was ataxia, and computed tomographic (CT) scan and magnetic resonance imaging (MRI) suggested a demyelinating disease of the cerebellum. Her cell-mediated immunity was impaired. At autopsy, the cerebellar disease was confirmed as PML by ultrastructural and immunohistochemical studies. Moreover, the JC type of papova virus infection was verified by Southern blot analysis.

引用

页码：218 / 223

页数：6

共 21 条

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