CYCLOSPORINE A THERAPY IN PARAPROTEIN-ASSOCIATED NEUROPATHY

被引：14

作者：

WATERSTON, JA ^{[1
]}

BROWN, MM ^{[1
]}

INGRAM, DA ^{[1
]}

SWASH, M ^{[1
]}

机构：

[1] LONDON HOSP,DEPT NEUROL,LONDON E1 1BB,ENGLAND

来源：

MUSCLE & NERVE | 1992年 / 15卷 / 04期

关键词：

CYCLOSPORINE-A; PARAPROTEIN; NEUROPATHY;

D O I：

10.1002/mus.880150404

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A case of IgG paraprotein-associated demyelinating neuropathy complicated by respiratory failure, which was unresponsive to standard immunosuppressive drug therapy, is reported. Cyclosporin A therapy resulted in a marked clinical recovery with objective improvement in nerve conduction and vital capacity. The beneficial response suggests that cell-mediated immunity is an important pathogenetic mechanism, and that cyclosporin A may be useful in the treatment of other refractory cases of paraprotein-associated neuropathy.

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页码：445 / 448

页数：4

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