INHIBITION OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE BY BENZYLAMINES .1. STRUCTURE-ACTIVITY RELATIONSHIPS

被引：56

作者：

FULLER, RW ^{[1
]}

MOLLOY, BB ^{[1
]}

DAY, WA ^{[1
]}

ROUSH, BW ^{[1
]}

MARSH, MM ^{[1
]}

机构：

[1] ELI LILLY & CO,LILLY RES LABS,INDIANAPOLIS,IN 46206

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1973年 / 16卷 / 02期

关键词：

D O I：

10.1021/jm00260a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：101 / 106

页数：6

共 12 条

[1] NEUROPHARMACOLOGICAL INVESTIGATION OF N-BENZYLSULFAMIDES [J].

AEBERLI, P ;

GOGERTY, J ;

HOULIHAN, WJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (04) :636-&

[2]

AXELROD J, 1962, J BIOL CHEM, V237, P1657

[3] AN ANTIMALARIAL ALKALOID FROM HYDRANGEA .14. SYNTHESIS OF 5-MONOSUBSTITUTED, 6-MONOSUBSTITUTED, 7-MONOSUBSTITUTED, AND 8-MONOSUBSTITUTED DERIVATIVES [J].

BAKER, BR ;

SCHAUB, RE ;

JOSEPH, JP ;

MCEVOY, FJ ;

WILLIAMS, JH .

JOURNAL OF ORGANIC CHEMISTRY, 1952, 17 (01) :141-148

[4]

CONNETT RJ, 1970, J BIOL CHEM, V245, P329

[5] INHIBITION OF PHENETHANOLAMINE N-METHYL TRANSFERASE BY RING-SUBSTITUTED ALPHA-METHYLPHENETHYLAMINES (AMPHETAMINES) [J].

FULLER, RW ;

MILLS, J ;

MARSH, MM .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (04) :322-&

[6] SUBSTRATE SPECIFICITY OF PHENETHANOLAMINE N-METHYL TRANSFERASE [J].

FULLER, RW ;

HUNT, JM .

BIOCHEMICAL PHARMACOLOGY, 1965, 14 (12) :1896-&

[7] A MICROMETHOD FOR ASSAY OF PHENETHANOLAMINE N-METHYL TRANSFERASE [J].

FULLER, RW ;

HUNT, JM .

ANALYTICAL BIOCHEMISTRY, 1966, 16 (02) :349-&

[8] INHIBITION OF ADRENAL PHENETHANOLAMINE-N-METHYLTRANSFERASE BY SUBSTITUTED IMIDAZOLES [J].

JENSEN, NP ;

SCHMITT, SM ;

SHEN, TY ;

WINDHOLZ, TB ;

LOPEZRAM.B ;

PORTER, CC ;

MANDEL, LR .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (04) :341-+

[9] PHENYLETHANOLAMINE-N-METHYLTRANSFERASE IN HUMAN ADRENAL GLAND [J].

KITABCHI, AE ;

WILLIAMS, RH .

BIOCHIMICA ET BIOPHYSICA ACTA, 1969, 178 (01) :181-&

[10] INHIBITION OF PHENYLETHANOLAMINE-N-METHYL TRANSFERASE [J].

KRAKOFF, LR ;

AXELROD, J .

BIOCHEMICAL PHARMACOLOGY, 1967, 16 (07) :1384-&

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