APPLICATION OF THE POLYMERASE CHAIN-REACTION FOR THE DETECTION OF HIV IN SPECIMENS FROM NEWBORN SCREENING PROGRAMS

被引：5

作者：

COMEAU, AM

机构：

[1] Theobald Smith Research Institute, Inc, State Laboratory Institute, Jamaica Plain, Massachusetts

来源：

ACTA PAEDIATRICA | 1994年 / 83卷

关键词：

HUMAN IMMUNODEFICIENCY VIRUS (HIV); POLYMERASE CHAIN REACTION (PCR); NEWBORN SCREENING;

D O I：

10.1111/j.1651-2227.1994.tb13330.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The use of the polymerase chain reaction (PCR) permits detection of HIV proviral DNA in the universally collected ''dried blood spot specimens'' of newborn screening programs. Detection of HIV proviral DNA among the annual cohorts of seropositive specimens from ongoing anonymous newborn HIV seroprevalence studies can provide a laboratory-based estimate of maternal-infant transmission rates. Preliminary data suggest that maternal-infant transmission rates may be higher in areas where the newborn seroprevalence rates are highest.

引用

页码：29 / 30

页数：2

共 2 条

[1] IDENTIFYING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AT BIRTH - APPLICATION OF POLYMERASE CHAIN-REACTION TO GUTHRIE CARDS [J].