METABOLISM OF COUMARIN IN MAN

被引:137
作者
SHILLING, WH
CRAMPTON, RF
LONGLAND, RC
机构
[1] British Industrial Biological Research Association, Carshalton, Surrey
关键词
D O I
10.1038/221664b0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Coumarin is a naturally occurring constituent of many plants, and has been used extensively as a flavouring material, although its use for this purpose is now banned in many countries. Its toxic effects on many species of animal have been reported1-6 and its metabolism in rats and rabbits has been investigated7-9. No study has been made of the metabolism of coumarin in man, and the work described here was undertaken to determine the similarity in this respect between man and rat or rabbit. © 1969 Nature Publishing Group.
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页码:664 / &
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