GABA-LIKE IMMUNOREACTIVITY IN TYPE-I GLOMERULI OF RAT SUBSTANTIA-GELATINOSA

被引：87

作者：

TODD, AJ

LOCHHEAD, V

机构：

[1] Department of Anatomy, University of Glasgow, Glasgow

来源：

BRAIN RESEARCH | 1990年 / 514卷 / 01期

关键词：

Lamina II; Presynaptic dendrite; Presynaptic inhibition; Spinal cord; Ultrastructure; γ-Aminobutyric acid;

D O I：

10.1016/0006-8993(90)90454-J

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A postembedding immunogold study of type I synaptic glomeruli in lamina II of rat dorsal horn was carried out using antiserum to γ-aminobutyric acid (GABA). Gold particles were concentrated over some peripheral axons and vesicle-containing dendrites within these glomeruli and both types of profile were presynaptic to central axons. These results suggest that GABA is involved in presynaptic inhibition of unmyelinated primary afferents and is released by some presynaptic dendrites within lamina II. © 1990.

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页码：171 / 174

页数：4

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