STRUCTURALLY BASED NEW FUNCTIONAL INTERPRETATIONS OF THE SUBSURFACE CISTERNAL NETWORK IN HUMAN OUTER HAIR-CELLS

被引：13

作者：

ARNOLD, W ^{[1
]}

ANNIKO, M ^{[1
]}

机构：

[1] UMEA UNIV,DEPT OTOLARYNGOL HEAD & NECK SURG,S-90187 UMEA,SWEDEN

来源：

ACTA OTO-LARYNGOLOGICA | 1990年 / 109卷 / 3-4期

关键词：

Function; Human; Morphology; Outer hair cell; Subsurface cisterns;

D O I：

10.3109/00016489009107436

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The system of subsurface cisterns (SSC) in human outer hair cells (OHC) was studied by high-resolution transmission electron microscopy (TEM). The SSC consist of only a single layer of cisterns, either flattened or tubular. The subsynaptic cisterns of efferent synapses are an integral part of the SSC. The outer leaflet of the SSC facing the cell membrane is connected to the OHC wall by pillars arranged in a highly regular and geometric pattern. The inner leaflet facing the cytoplasm displays an identical pattern of particles arranged in a star-like configuration so that pores are formed centrally. Pores are also identified at the outer leaflet and at the insertion of the pillars into the cell membrane. It is hypothesized that this highly specific organization of SSC, so far described only in the human OHC wall, is controlled by the efferent acetylcholine-mediated innervation. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：213 / 220

页数：8

共 20 条

[1] SUPPORTING AND MEMBRANE STRUCTURES OF HUMAN OUTER HAIR-CELLS - EVIDENCE FOR AN ISOMETRIC CONTRACTION [J].

ARNOLD, W ;

ANNIKO, M .

ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 1989, 51 (06) :339-353

[2]

BOBBIN RP, 1984, RECENT ADV HEARING S, P159

[3] EVOKED MECHANICAL RESPONSES OF ISOLATED COCHLEAR OUTER HAIR-CELLS [J].

BROWNELL, WE ;

BADER, CR ;

BERTRAND, D ;

DERIBAUPIERRE, Y .

SCIENCE, 1985, 227 (4683) :194-196

[4]

BROWNELL WE, 1984, SCANNING ELECTRON MI, V3, P1401

[5]

BRUNDIN L, 1989, 2LTH INN EAR BIOL WO, P27

[6] MECHANISMS OF MOVEMENT IN OUTER HAIR-CELLS AND A POSSIBLE STRUCTURAL BASIS [J].

FLOCK, A ;

FLOCK, B ;

ULFENDAHL, M .

ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 1986, 243 (02) :83-90

[7] STIMULATION OF NEURONAL ACETYLCHOLINE-RECEPTORS INDUCES RAPID GENE-TRANSCRIPTION [J].

GREENBERG, ME ;

ZIFF, EB ;

GREENE, LA .

SCIENCE, 1986, 234 (4772) :80-83

[8] THE ION CHANNEL OF THE NICOTINIC ACETYLCHOLINE-RECEPTOR [J].

GUY, HR ;

HUCHO, F .

TRENDS IN NEUROSCIENCES, 1987, 10 (08) :318-321

[9]

HOLLEY MC, 1988, 25TH INN EAR BIOL WO, P24

[10] STIMULATED ACOUSTIC EMISSIONS FROM WITHIN HUMAN AUDITORY-SYSTEM [J].

KEMP, DT .

JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 1978, 64 (05) :1386-1391

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