VIRIDANS STREPTOCOCCAL BACTEREMIA IN PATIENTS WITH HEMATOLOGICAL AND SOLID MALIGNANCIES

被引：41

作者：

BURDEN, AD

OPPENHEIM, BA

CROWTHER, D

HOWELL, A

MORGENSTERN, GR

SCARFFE, JH

THATCHER, N

机构：

[1] WITHINGTON HOSP, DEPT MICROBIOL, W DIDSBURY, MANCHESTER M20 8LR, LANCS, ENGLAND

[2] CHRISTIE HOSP & HOLT RADIUM INST, DEPT MED ONCOL, MANCHESTER M20 9BX, LANCS, ENGLAND

[3] CHRISTIE HOSP & HOLT RADIUM INST, DEPT HAEMATOL, MANCHESTER M20 9BX, LANCS, ENGLAND

[4] CHRISTIE HOSP & HOLT RADIUM INST, DEPT MICROBIOL, MANCHESTER M20 9BX, LANCS, ENGLAND

来源：

EUROPEAN JOURNAL OF CANCER | 1991年 / 27卷 / 04期

关键词：

D O I：

10.1016/0277-5379(91)90373-L

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Thirty-three episodes of septicaemia caused by viridans streptococci are reported in 32 adults under treatment for malignant diseases. The underlying diseases were acute leukaemia (17), lymphoma (4), myeloma (1), small cell carcinoma of the bronchus (6), carcinoma of the breast (2) and carcinoma of the stomach (2). Important predisposing factors included severe neutropenia and oral mucositis due to intensive chemotherapeutic regimens. There was a poor response to standard empirical antibiotics and a mortality of 12%. A role for prophylactic penicillin in high risk groups is suggested.

引用

页码：409 / 411

页数：3

共 9 条

[1] RANDOMIZED TRIAL COMPARING CIPROFLOXACIN PLUS NETILMICIN VERSUS PIPERACILLIN PLUS NETILMICIN FOR EMPIRIC TREATMENT OF FEVER IN NEUTROPENIC PATIENTS [J].