MERCURIC-CHLORIDE INDUCED-INHIBITION OF ACID AND ALKALINE-PHOSPHATASE ACTIVITY IN THE KIDNEY OF MUDSKIPPER, BOLEOPHTHALMUS-DENTATUS

被引:18
作者
LAKSHMI, R [1 ]
KUNDU, R [1 ]
THOMAS, E [1 ]
MANSURI, AP [1 ]
机构
[1] SAURASHTRA UNIV,DEPT BIOSCI,MARINE BIOL LAB,RAJKOT 360005,GUJARAT,INDIA
来源
ACTA HYDROCHIMICA ET HYDROBIOLOGICA | 1991年 / 19卷 / 03期
关键词
D O I
10.1002/aheh.19910190314
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The present paper deals with the inhibition of the specific activity of the acid and alkaline phosphatases in the kidney tissue of mudskipper Boleophthalmus dentatus, exposed to different sublethal concentrations of mercuric chloride. There was a more or less linear inhibition of the specific activity of both the enzymes with increasing concentration of mercuric chloride as well as exposure time. The inhibition of acid phosphatase could be due to the rupture of lysosomal membrane in the presence of mercury compound, which acts as a labilizing agent. The inhibition of alkaline phosphatase probably caused a breakdown of the membrane transport system.
引用
收藏
页码:341 / 344
页数:4
相关论文
共 15 条
[1]  
Fiske C.F., Subbarow Y., The colorimetric determination of phosphorus, J. Biol. Chem., 66, (1925)
[2]  
Fowler B.A., Brown H.W., Lucier G.W., Beard M.E., Mercury uptake by renal lysosomes of rats ingesting methylmercury hydroxide. Ultrastructural observations and energy dispersive x‐Ray analysis, Arch. Pathol., 98, (1974)
[3]  
Friede R.L., Topographic Brain Chemistry, (1966)
[4]  
Hinton D., Koening J.C., Acid phosphatase activity in the subcellular fractions of fish liver exposed to methylmercury chloride, Comp. Biochem. Physiol., 59, (1975)
[5]  
Hossain A., Dutta H.M., Acid phosphatase activity in the intestine and the caeca of bluegill exposed to methylmercury chloride, Bull. Environm. Contam. Toxicol., 36, (1986)
[6]  
Lin C.W., Sasaki M., Orcutt M.L., Migayama H., Singer K.M., Plasma phosphatases in the He La cells, J. Histochem. Cytochem., 23, (1976)
[7]  
Lojda Z., Gossrau R., Schiebler T.H., Enzyme Histochemistry. A Laboratory Manual, (1979)
[8]  
Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J., Protein estimation measurement with the Folin—phenol reagent, J. Biol. Chem., 193, (1951)
[9]  
Miyakawa T., Mechanism of pathological changes of cells induced by organic mercury compounds in Minamata disease, Adv. neurol. Sci., 17, (1973)
[10]  
Novikoff A.B., Lysosomes and related particles, The Cell, 2, (1961)