MAGNETIC-RESONANCE-IMAGING OF BRAIN AND THE NEUROMOTOR DISORDER IN ENDEMIC CRETINISM

被引：23

作者：

MA, T

LIAN, ZC

QI, SP

HEINZ, ER

DELONG, GR

机构：

[1] DUKE UNIV,MED CTR,DEPT PEDIAT,DIV PEDIAT NEUROL,BOX 3533,DURHAM,NC 27710

[2] TIANJIN MED COLL,TIANJIN,PEOPLES R CHINA

[3] DUKE UNIV,MED CTR,DEPT RADIOL,DIV NEURORADIOL,DURHAM,NC 27710

来源：

ANNALS OF NEUROLOGY | 1993年 / 34卷 / 01期

关键词：

D O I：

10.1002/ana.410340116

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neurological endemic cretinism, resulting from severe iodine deficiency, is characterized by mental deficiency, deaf-mutism, and a spastic-rigid motor disorder. Its neuropathology and pathophysiology have been investigated very little. We report the clinical and magnetic resonance imaging brain scan findings of 3 adult Chinese cretins. All show an apparent magnetic resonance imaging abnormality in the globus pallidus and substantia nigra, with hyperintensity on T1-weighted images and hypointensity on T2-weighted images. The motor abnormality, characterized by truncal and proximal limb-girdle rigidity and spasticity, with relative sparing of the hands and feet, is analogous to other extrapyramidal disorders. Endemic cretinism is a unique form of cerebral palsy of potential interest for students of human neuromotor development.

引用

页码：91 / 94

页数：4

共 21 条

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