A UNIVERSAL SOLID SUPPORT FOR THE SYNTHESIS OF 3'-THIOL GROUP CONTAINING OLIGONUCLEOTIDES

被引:39
作者
GUPTA, KC
SHARMA, P
SATHYANARAYANA, S
KUMAR, P
机构
[1] Nucleic Acids Research Laboratory, CSIR Centre for Biochemicals, Delhi, 110 007, V.P.Chest Institute Building
关键词
D O I
10.1016/S0040-4039(00)97392-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Use of a derivatised polymer support 5 involving the 4,4′-dimethoxytrityloxypentyl-3-mercaptopropionamide group allows the automated synthesis of oligonucleotides bearing thiol group at their 3′-termini. © 1990.
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页码:2471 / 2474
页数:4
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