DETERMINATION OF CREATININE-RELATED URINARY URACIL EXCRETION IN CHILDREN BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：5

作者：

ASSMANN, B ^{[1
]}

HAAS, HJ ^{[1
]}

机构：

[1] UNIV SAARLAND,FACHRICHTUNG PHYSIOL CHEM,W-6650 HOMBURG,GERMANY

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1990年 / 525卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)83404-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Excretion rates of uracil and thymine in children (n = 140) and circadian rhythms of urinary uracil excretion (n = 9) were investigated by reversed-phase high-performance liquid chromatography with ultraviolet detection. Excretion values were related to urinary creatinine determined by Jaffé's method. Creatinine-related uracil excretion was not dependent on age or sex. The values seemed to be distributed according to a Gaussian graph in both school children and those in hospital. The intra-individual range was 1.32-23.70 mg uracil per g creatinine over a four-day period in one subject. Uracil excretion seems to be somewhat lower during the night. © 1990.

引用

页码：277 / 285

页数：9

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