ENDOCRINE PROFILE ASSOCIATED WITH ESTROGEN AND PROGESTERONE RECEPTORS IN LEIOMYOMA AND NORMAL MYOMETRIUM

被引:6
作者
SADAN, O [1 ]
VANIDDEKINGE, B [1 ]
SAVAGE, N [1 ]
VANDERWALT, LA [1 ]
ZAKUT, H [1 ]
机构
[1] TEL AVIV UNIV,EDITH WOLFSON MED CTR,SACKLER FAC MED,DEPT OBSTET & GYNECOL,POB 5,IL-58100 HOLON,ISRAEL
关键词
D O I
10.3109/09513599009030689
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In leiomyoma and normal myometrium estrogen receptors act independently at low or high levels of the normal serum steroid range in the menstrual cycle. It might be an inherent characteristic of leiomyomas, which results in their progressive growth in the absence of any abnormal stimulation. In the secretory phase of the menstrual cycle, serum progesterone suppresses estrogen receptor concentrations in leiomyoma. In the present study serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) showed direct as well as inverse correlations with estrogen and progesterone receptors in different phases of the menstrual cycle. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:33 / 42
页数:10
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