TOLYTOXIN AND NEW SCYTOPHYCINS FROM 3 SPECIES OF SCYTONEMA

被引：108

作者：

CARMELI, S ^{[1
]}

MOORE, RE ^{[1
]}

PATTERSON, GML ^{[1
]}

机构：

[1] UNIV HAWAII, DEPT CHEM, HONOLULU, HI 96822 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1990年 / 53卷 / 06期

关键词：

D O I：

10.1021/np50072a021

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Tolytoxin [1], the major cytotoxin associated with Scytonema mirabile strain BY-8-1, Scytonema burmanicum strain DO-4-1 and Scytonema ocellatum strains DD-8-1, FF-65-1, and FF-66-3, has been shown to be 6-hydroxy-7-0-methylscytophycin B. Minor amounts of three other new cytotoxic scytophycins, 6-hydroxyscytophycin B [2], 19-0-demethylscytophycin C [3], and 6-hydroxy-7-0-methylscytophycin E [4], have also been isolated from these cyanophytes. The gross structures and stereochemistry are based on nmr and cd analysis and on comparison with scytophycins A-E.

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页码：1533 / 1542

页数：10

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