BETA-DIETHOXYPHOSPHORYLPROPIONIC ACID, A CONVENIENT REAGENT FOR THE SYNTHESIS OF BETA,GAMMA-UNSATURATED AMIDES

被引：8

作者：

JANECKI, T ^{[1
]}

BODALSKI, R ^{[1
]}

机构：

[1] TECH UNIV LODZ,INST ORGAN CHEM,PL-90924 LODZ,POLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 43期

关键词：

D O I：

10.1016/0040-4039(91)80796-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Beta-Diethoxyphosphorylpropionic acid (1) is converted into delta-substituted beta-(diethoxyphosphoryl)-delta-lactones 5 by LDA promoted reaction with carbonyl compounds 3. Aminolysis or alternatively a standard alkylation and aminolysis of 5 afford (E)-beta,delta-unsaturated amides 7 or 10 in good yield.

引用

页码：6231 / 6234

页数：4

共 19 条

[1]

AVOGARA P, 1977, ARTERY, P219

[2]

CANONIA L, 1966, Patent No. 3231469

[3]

HAEBERLE N, 1980, Patent No. 2830351

[4]

JANECKI T, 1989, SYNTHESIS-STUTTGART, P506