PRIMARY STRUCTURE OF THE ASIALO-CARBOHYDRATE UNITS OF THE 1ST GLYCOSYLATION SITE OF HUMAN-PLASMA ALPHA-1-ACID GLYCOPROTEIN

被引：77

作者：

SCHMID, K

BINETTE, JP

DORLAND, L

VLIEGENTHART, JFG

FOURNET, B

MONTREUIL, J

机构：

[1] STATE UNIV UTRECHT, DEPT BIOORGAN CHEM, UTRECHT, NETHERLANDS

[2] UNIV LILLE 1, CHIM BIOL LAB, F-59650 VILLENEUVE DASCQ, FRANCE

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 581卷 / 02期

关键词：

(Human plasma); Carbohydrate structure; Glycosylation site; α[!sub]1[!/sub]-Acid glycoprotein;

D O I：

10.1016/0005-2795(79)90255-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The elucidation of the structures of the carbohydrate units linked to glycosylation site I of human plasma α1-acid glycoprotein is described. These carbohydrate units can be grouped into compounds with bi- (class A) and triantennary (class B) structures and the triantennary structure with a fucose residue (class BF) (Fig. 1). The structural variability of the carbohydrate units of glycosylation site I and also of glycosylation sites II to V (Fournet, B., Montreuil, J., Strecker, G., Dorland, L., Haverkamp, J., Vliegenthart, J.F.G., Binette, J.P. and Schmid, K. (1978) Biochemistry 17, 5206-5214) accounts largely for the microheterogeneity of α1-acid glycoprotein. © 1979.

引用

页码：356 / 359

页数：4

共 6 条

[1] STRUCTURE OF ASIALO-CARBOHYDRATE UNITS OF HUMAN SEROTRANSFERRIN AS PROVEN BY 360 MHZ PROTON MAGNETIC-RESONANCE SPECTROSCOPY [J].