ENZYMATIC OXIDATION OF PHENOLIC "TETRAHYDROISOQUINOLINE-1-CARBOXYLIC ACIDS

被引：21

作者：

COUTTS, IGC ^{[1
]}

HAMBLIN, MR ^{[1
]}

TINLEY, EJ ^{[1
]}

BOBBITT, JM ^{[1
]}

机构：

[1] UNIV CONNECTICUT,DEPT CHEM,STORRS,CT 06268

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 11期

关键词：

D O I：

10.1039/p19790002744

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tetrahydroisoquinoline-1 -carboxylic acids with a 6- or 7-hydroxy substituent undergo oxidative decarboxylation on treatment with horseradish peroxidase or fungal laccase to give high yields of the corresponding 3,4-dihydroisoquinolines. Attempts to apply this reaction to the formation of an aporphine were unsuccessful.

引用

页码：2744 / 2750

页数：7

共 35 条

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BENFIELD, G
BOCKS, SM
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[5] ELECTROCHEMISTRY OF NATURAL-PRODUCTS .6. OXIDATIVE DECARBOXYLATION OF SOME "TETRAHYDROISOQUINOLINE-1-CARBOXYLIC ACIDS
BOBBITT, JM
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[6] BOBBITT JM, 1976, HETEROCYCLES, V4, P1645
[7] BOBBITT JM, 1976, 6TH NAT PROD S U W I
[8] BOCKS S. M., 1963, TETRAHEDRON, V19, P1109, DOI 10.1016/S0040-4020(01)99366-4
[9] SYNTHESIS AND CHARACTERIZATION OF 6- AND 7-METHOXY-1-BENZYL-2-METHYL-1,2,3,4-TETRAHYDRO-6-AND 7-ISOQUINOLINOLS
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RACHLIN, AI
TEITEL, S
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1967, 4 (03) : 417 - &
[10] SYNTHESEN IN DER ISOCHINOLINREIHE ZUR PARTIELLEN ATHERSPALTUNG 6,7-DIMETHOXY-SUBSTITUIERTER 3,4-DIHYDRO-ISOCHINOLINE UND ISOCHINOLINE
BRUDERER, H
BROSSI, A
[J]. HELVETICA CHIMICA ACTA, 1965, 48 (08) : 1945 - &

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