ELEVATED ARTERIAL BLOOD-PRESSURE IN CARDIAC-TAMPONADE

Background. In cardiac tamponade cardiac output falls, but peripheral vascular resistance increases, so that systemic blood pressure may be maintained at normal or near-normal levels. We recently observed a patient with cardiac tamponade whose blood pressure was markedly elevated. Methods. To determine the frequency of elevated blood pressure in patients with cardiac tamponade and their hemodynamic characteristics, we studied 18 consecutive patients with cardiac tamponade from a variety of causes using right heart catheterization. Results. Six of the 18 patients had systolic arterial blood pressures ranging from 150 to 210 mm Hg (mean [+/-SD], 176+/-26) and diastolic pressures ranging from 100 to 130 mm Hg (mean, 113+/-14). All six had previously been hypertensive. After pericardiocentesis there was a significant decrease in blood pressure (to 139+/-13 mm Hg systolic, P<0.05; and 83+/-6 mm Hg diastolic, P<0.01) and peripheral vascular resistance (from 2150+/-588 to 1207+/-345 dyn . sec . cm-5, P<0.01). Cardiac output increased in all six. The other 12 patients, 3 of whom had a history of hypertension, had significant increases in cardiac output and systolic blood pressure (from 119+/-13 to 127+/-7 mm Hg, P<0.05) after pericardiocentesis, whereas peripheral vascular resistance decreased. Both groups had similar degrees of cardiac tamponade, as indicated by measurements of cardiac output and intrapericardial, right atrial, and pulmonary-artery wedge pressures. Conclusions. Elevated blood pressure may occur in some patients with cardiac tamponade who have preexisting hypertension. Moreover, blood pressure may fall after pericardiocentesis in patients who have elevated blood pressure associated with tamponade.